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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1522796Generated: November 2, 2026

p-Toluenesulfonic acid → (5R)-5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione tosylate

https://huagongshe.com/reaction/1522796

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Toluenesulfonic acidHCID 6101—
Reactant5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione (-)-O,O'-dibenzoyl-L-tartrateHCID 86731963—
SolventIsopropanolHCID 3776—
Product(5R)-5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione tosylateHCID 86651734—

Reaction Steps

To a solution of p-toluenesulphonic acid (0.8 g) in IPA (12 mL) at 40° C. was added R)-5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione (−)-O,O′-dibenzoyl-L-tartrate

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09078885B2
Source datasetuspto-grants-2015_07
ORD IDord-4f690bce795c443c8b1c33b7496dd9d2
Source noteuspto-grants-2015_07