Methanol → D-Glucose

The solution was diluted with MeOH (3.0 mL, total volume: 3.5 mL) and the pH value was adjusted to 1 by addition of trifluoroacetic acid. An aqueous solution of HAuCl4 (331 mL, 0.025M) was added. Then, 1N aqueous solution of NaBH4 (182 μL) was added in several portions with rapid shaking. The black suspension formed was shaken for an additional 2 h and the methanolic layer was separated by decantation[2]. The black solid was dissolved in water (700 μL) and purified by centrifugal filtering (AMICON MW 10000, 30 min, 14000 rpm). The process was repeated twice, until the nanoparticles were free of salts and starting materials. The residue in the AMICON filter was dissolved in 500 μL of water and lyophilised to afford 0.7 mg of BMIX V nanoparticles. TEM: average diameter 1.64 nm, 140 gold atoms, 53 chains, MW=45568.

1. customThe black suspension formed
2. customthe methanolic layer was separated by decantation[2]
3. dissolutionThe black solid was dissolved in water (700 μL)
4. custompurified
5. filtrationby centrifugal filtering (AMICON MW 10000, 30 min, 14000 rpm)
6. filtrationThe residue in the AMICON filter
7. dissolutionwas dissolved in 500 μL of water
8. customto afford 0.7 mg of BMIX V nanoparticles

ORD record

ord-f50d3ea686334b249ab38f28a0aad709

Source dataset

uspto-grants-2015_07

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US09079765B2