HRID1522966

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7054

Isatin

C8H5NO2

HCID240039

Cyclohexanecarbohydrazide

C7H14N2O

PRODUCTS

产物

$反应SMILES：CCCCCCN1C(=O)/C(=N\NC(=O)C2CCCCC2)c2ccccc21$

HCID178444724

未命名化合物

收率 45%

PROCEDURE

实验过程

The title compound was prepared as a yellow solid, using isatin 3 and cyclohexanecarbohydrazide according to the synthetic method E. The resulting solid was washed with ethanol. Yield: 45%. 1H NMR (DMSO-d6): δ δ 0.85 (t, J=6.8 Hz, 3H), 1.24-1.83 (m, 19H), 3.74 (t, J=6.9 Hz, 2H), 7.15 (t, J=7.5 Hz, 1H), 7.19 (d, J=7.8 Hz, 1H), 7.45 (t, J=7.8 Hz, 1H), 7.48 (d, J=7.5 Hz, 1H), 7.59 (d, 3H), 12.34 (br s, isomer 1: 50%, 0.5; H), 13.00 (br s, isomer 2: 50%, 0.5; H), both isomer are in the same proportion. 13C NMR (DMSO-d6): δ 14.33(CH3), 22.42 (CH2), 25.48 (CH2), 26.34 (CH2), 25.83 (CH2), 27.37 (CH2), 31.29 (CH2), 39.64 (CH2), 110.52 (CH), 119.78 (C), 123.48 (CH), 131.79 (CH), 143.27 (C═N), (C═O). HRMS (ES+) calcd for C21H30N3O2 (M+H+), m/e, 356.2328. found, 356.2333.

WORKUP

后处理

washThe resulting solid was washed with ethanol