Isatin → 1-(3-methylbutyl)-1H-indole-2,3-dione

HRID 1523017노트

반응식

HRID 1523017 반응식
C(N1[C:12]2[C:7](=[CH:8]C=CC=2)[C:6](=O)[C:5]1=O)CC.[NH:15]1[C:25]2[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=2)[C:18](=[O:19])[C:16]1=[O:17].BrCCC(C)C>>[CH2:5]([N:15]1[C:25]2[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=2)[C:18](=[O:19])[C:16]1=[O:17])[CH2:6][CH:7]([CH3:12])[CH3:8]

참가 물질

4

반응물 3

HCID 7054IsatinHCID 78911-Bromo-3-methylbutaneHCID 16450901-propyl-1H-indole-2,3-dione

생성물 1

HCID 23625931-(3-methylbutyl)-1H-indole-2,3-dione

실험 절차

Was prepared in an analogous manner to 1-propylindoline-2,3-dione using commercially available isatin (purchased from Fisher Scientific) and 1-bromo-3-methyl butane (purchased from Fisher Scientific). 1H NMR δ 7.58 (m, 2H), 7.10 (t, 1H), 6.89 (d, 1H), 3.73 (t, 2H), 1.58 (m, 3H), 1.00 (d, 6H).

출처 및 근거

ORD 기록
ord-401d89f33ab4468e99184d03d59d605a
출처 데이터셋
uspto-grants-2015_07
특허 번호
US09079853B2

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