1-Bromo-2-methylpropane → 1-(2-methylpropyl)-2,3-dihydro-1H-indole-2,3-dione

HRID 1523023Notes

Reaction equation

HRID 1523023 reaction equation
[CH2:1]([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6](=[O:13])[C:5]1=[O:14])[CH2:2][CH3:3].N1C2C(=CC=CC=2)C(=O)[C:16]1=O.BrCC(C)C>>[CH2:1]([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6](=[O:13])[C:5]1=[O:14])[CH:2]([CH3:16])[CH3:3]

Participants

4

Reactant 3

HCID 65551-Bromo-2-methylpropaneHCID 7054IsatinHCID 16450901-propyl-1H-indole-2,3-dione

Product 1

HCID 23872331-(2-methylpropyl)-2,3-dihydro-1H-indole-2,3-dione

Procedure

Was prepared in an analogous manner to 1-propylindoline-2,3-dione using isatin (purchased from Fisher Scientific) and 1-bromo-2-methyl propane (purchased from Fisher Scientific). 1H NMR δ (dd, 2H), 7.13 (t, 1H), 6.90 (d, 1H), 3.55 (d, 2H), 2.16 (m, 1H), 1.00 (d, 6H).

Sources & evidence

ORD record
ord-08e3d77851ae4485a3dfd94af8884dd5
Source dataset
uspto-grants-2015_07
Patent number
US09079853B2

Reaction notes

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