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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1523041Generated: October 30, 2026

1-Bromo-3-methylbutane → 5-Chloro-1-isopentylindoline-2,3-dione

https://huagongshe.com/reaction/1523041

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-3-methylbutaneHCID 7891—
Reactant5-chloro-1H-indole-2,3-dioneHCID 87203—
Reactant1-propyl-1H-indole-2,3-dioneHCID 1645090—
Product5-Chloro-1-isopentylindoline-2,3-dioneHCID 4736864—

Reaction Steps

This compound was prepared in a similar method as 1-propylindoline-2,3-dione by reacting commercially available 5-chloro isatin (purchase from Fisher Scientific) with commercially available 1-bromo-3-methylbutane (purchase from Fisher Scientific). 1H NMR δ 7.57 (m, 2H), 6.85 (d, 1H), 3.73 (t, 2H), 1.57 (m, 3H), 1.00 (d, 6H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09079853B2
Source datasetuspto-grants-2015_07
ORD IDord-8632056b8ea543418ffaf0e783f05959
Source noteuspto-grants-2015_07