Tetrahydrofuran → 5-bromo-1H-pyrrolo[2,3-b]pyridine

HRID 152325Notes

Reaction equation

HRID 152325 reaction equation
[Br:19][c:20]1[cH:21][c:22]2[c:23]([n:24][cH:25]1)[n:26]([Si:29]([C:30]([CH3:31])([CH3:32])[CH3:33])([CH3:34])[CH3:35])[cH:27][cH:28]2.[CH3:2][CH2:3][CH2:4][CH2:5][N+:6]([CH2:7][CH2:8][CH2:9][CH3:10])([CH2:11][CH2:12][CH2:13][CH3:14])[CH2:15][CH2:16][CH2:17][CH3:18].[F-:1].[O:36]1[CH2:37][CH2:38][CH2:39][CH2:40]1>>[Br:19][c:20]1[cH:21][c:22]2[c:23]([n:24][cH:25]1)[nH:26][cH:27][cH:28]2

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 16028TetrabutylammoniumHCID 28179Fluoride IonHCID 497590181H-Pyrrolo[2,3-B]pyridine, 5-bromo-1-[(1,1-dimethylethyl)dimethylsilyl]-

Product 1

HCID 103079325-bromo-1H-pyrrolo[2,3-b]pyridine

Sources & evidence

ORD record
ord-645cb44caac449a5b44b9e396449f5fb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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