Hydrochloric Acid → 2-({5-[(Azetidin-3-yloxy)methyl]-6-methylpyridin-2-yl}amino)-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide
Reaction equation
[CH3:45][C:46]#[N:47].[ClH:42].[NH2:1][C:2](=[O:3])[c:4]1[c:5]([NH:21][c:22]2[cH:23][cH:24][c:25]([CH2:29][O:30][CH:31]3[CH2:32][N:33]([C:35]([O:36][C:37]([CH3:38])([CH3:39])[CH3:40])=[O:41])[CH2:34]3)[c:26]([CH3:28])[n:27]2)[s:6][c:7](-[c:9]2[c:10]([F:20])[cH:11][c:12]([C:16]([CH3:17])([CH3:18])[OH:19])[cH:13][c:14]2[F:15])[cH:8]1.[Na+:44].[OH-:43]>>[NH2:1][C:2](=[O:3])[c:4]1[c:5]([NH:21][c:22]2[cH:23][cH:24][c:25]([CH2:29][O:30][CH:31]3[CH2:32][NH:33][CH2:34]3)[c:26]([CH3:28])[n:27]2)[s:6][c:7](-[c:9]2[c:10]([F:20])[cH:11][c:12]([C:16]([CH3:17])([CH3:18])[OH:19])[cH:13][c:14]2[F:15])[cH:8]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-70a6c48924284aafa5bb406c47a7130a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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