HRID1523869

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CN([C@H]1CCCN(C(=O)OC(C)(C)C)C1)S(=O)(=O)c1ccccc1Br

HCID90312865

未命名化合物

结构：CC1(C)OB(c2ccc(-c3cnc(N)nc3)c(F)c2)OC1(C)C

HCID90313142

未命名化合物

PRODUCTS

生成物

结构：CN([C@H]1CCCNC1)S(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)nc2)c(F)c1

HCID90314017

未命名化合物

PROCEDURE

实验过程

The title compound was prepared using methods analogous to those described in Example 376 using 5-(2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pyrimidin-2-amine and (S)-tert-butyl 3-(2-bromo-N-methylphenylsulfonamido)-piperidine-1-carboxylate yielding 41 mg (48%) of the title compound after HPLC purification. MS (ESI): mass calcd. for C27H32FN5O4S, 541.21; m/z found, 542.1 [M+H]+.

WORKUP

后处理

customThe title compound was prepared
customafter HPLC purification