HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-5-bromopyrimidine → 5-(4-Bromo-2,3-difluorophenyl)pyrimidin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-5-bromopyrimidine | HCID 231310 | — |
| Reactant | 4-Bromo-2,3-difluorobenzeneboronic acid | HCID 2773292 | — |
| Solvent | 5-(4-Chloro-2-fluorophenyl)pyrazin-2-amine | HCID 80200485 | — |
| Product | 5-(4-Bromo-2,3-difluorophenyl)pyrimidin-2-amine | HCID 90314254 | — |
Reaction Steps
The title compound was prepared using analogous conditions to those described in 5-(4-chloro-2-fluorophenyl)pyrazin-2-amine using (4-bromo-2,3-difluorophenyl)boronic acid and 5-bromopyrimidin-2-amine. MS (ESI): mass calcd. for C10H6BrF2N3, 284.97; m/z found, 286.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09079866B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-994f2e239f1149258e1951bfe6ef41df |
| Source note | uspto-grants-2015_07 |