Trifluoroacetic acid → HCID 67117203, compound

HRID 1525097Notes

Reaction equation

HRID 1525097 reaction equation
[CH3:1][C:2]1[N:7]=[CH:6][N:5]=[C:4]([N:8]2[CH2:12][CH:11]3[CH2:13][N:14](C(OC(C)(C)C)=O)[CH2:15][CH:10]3[CH2:9]2)[N:3]=1.C(O)(C(F)(F)F)=O>C(Cl)Cl>[CH3:1][C:2]1[N:7]=[CH:6][N:5]=[C:4]([N:8]2[CH2:9][CH:10]3[CH:11]([CH2:13][NH:14][CH2:15]3)[CH2:12]2)[N:3]=1

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 86669175HCID 86669175, compound

Product 1

HCID 67117203HCID 67117203, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

tert-Butyl 5-(4-methyl-1,3,5-triazin-2-yl)hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate (43 mg, 0.142 mmol), DCM (1.4 mL) and TFA (0.71 mL) were stirred at room temperature for 2 h. The mixture was concentrated in vacuo and taken on to the next step without further purification.

Workup

  1. concentrationThe mixture was concentrated in vacuo
  2. customtaken on to the next step without further purification

Sources & evidence

ORD record
ord-ef28abd141544f988f8d19080f1fbf0b
Source dataset
uspto-grants-2015_07
Patent number
US09079911B2

Reaction notes

Loading…