反应详情

温度

25 °C

To a 100 mL autoclave with a stirrer, trans-RuCl2[(R)-dm-segphos][(S)-daiPen] (3.6 mg, 0.003 mol, 1/1,000 molar fold of 1-tetralone) was added. After purging with nitrogen, 2-propanol (3 mL), 1-tetralone (439 mg, 3 mmol) and 2-propanol solution of t-BuOK (0.1 mol/L, 0.3 mL, 0.03 mmol) were added. Subsequently, purging with hydrogen, the mixture was stirred at 25° C. for 15 hours under hydrogen pressure of 1 MPa. As a result of analysis of the reaction solution by using gas chromatography (Chirasil-DEX CB), it was found that the conversion rate is 42% and the optical purity is 90% ee.

1. additionwere added
2. customSubsequently, purging with hydrogen
3. customAs a result of analysis of the reaction solution