反应详情

Thereto, 2-octadecyn-1-ol (510 mg) was dissolved in dichloromethane (20 mL) and carbontetrabromide (960 mg) and triphenylphosphine (660 mg) were added at 0° C., followed by stirring at room temperature for 2 hours. The reaction solution was concentrated under reduced pressure and the obtained residue was purified by silica gel column chromatography (hexane:ethyl acetate-99:1→95:5) to obtain the title compound (630 mg) having the following physical property values.

1. concentrationThe reaction solution was concentrated under reduced pressure
2. customthe obtained residue was purified by silica gel column chromatography (hexane:ethyl acetate-99:1→95:5)