HRID152624

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11

1,2-Dichloroethane

C2H4Cl2

HCID1049

Pyridine

C5H5N

HCID14284

4-(Dimethylamino)pyridine

C7H10N2

HCID75771

1-Hydroxybenzotriazole

C6H5N3O

HCID2795515

4-(pyrrolidin-1-yl)benzoic acid

C11H13NO2

HCID6496943

[4-(Aminomethyl)phenyl]methanol

C8H11NO

PRODUCTS

产物

HCID11312933

N-(4-Hydroxymethylbenzyl)-4-pyrrolidin-1-ylbenzamide

C19H22N2O2

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-e8006ae546d24a56906b99522998de49
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (9/10)

反应SMILES

[CH2:35]([Cl:36])[CH2:37][Cl:38].[CH3:39][N:40]([c:41]1[cH:42][cH:43][n:44][cH:45][cH:46]1)[CH3:47].[N:1]1([c:6]2[cH:7][cH:8][c:9]([C:10](=[O:11])[OH:12])[cH:13][cH:14]2)[CH2:2][CH2:3][CH2:4][CH2:5]1.[NH2:15][CH2:16][c:17]1[cH:18][cH:19][c:20]([CH2:23][OH:24])[cH:21][cH:22]1.[OH:25][n:26]1[c:27]2[cH:28][cH:29][cH:30][cH:31][c:32]2[n:33][n:34]1.[cH:48]1[cH:49][cH:50][n:51][cH:52][cH:53]1>>[N:1]1([c:6]2[cH:7][cH:8][c:9]([C:10](=[O:12])[NH:15][CH2:16][c:17]3[cH:18][cH:19][c:20]([CH2:23][OH:24])[cH:21][cH:22]3)[cH:13][cH:14]2)[CH2:2][CH2:3][CH2:4][CH2:5]1