Hydrochloric Acid → HCID 117770030, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 4-chloro-1-(2,6-difluorophenyl)-2-oxo-1,2-dihydropyridine-3-carbaldehyde obtained in Step C (1.07 g), hydroxylamine hydrochloride (414 mg), conc. hydrochloric acid (0.0120 mL) and 2-propanol (10 mL) was heated at 100° C. for 2 hr, and cooled to room temperature. The resulting solid was collected by filtration, and dried under reduced pressure to give the title compound (800 mg).

Provenance & Evidence