HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 89775215, compound → HCID 117770487, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 89775215 | HCID 89775215 | — |
| Solvent | Ethanol hexane | HCID 21879635 | — |
| Product | HCID 117770487 | HCID 117770487 | 48.5% |
Reaction Steps
Racemic 3-amino-7-bromo-5-(1-cyclopropylethyl)-1,5-dihydro-4H-pyrazolo[4,3-c]pyridin-4-one obtained in Example 164 (1.1 g) was resolved by HPLC (column: CHIRALPAD AD, 50 mmID×500 mmL, manufactured by Daicel Chemical Industries, mobile phase: hexane/ethanol=800/200(v/v)) to give the title compound (533 mg) having a shorter retention time.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09085578B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-ed1bd9d7a953409cb91c9bf769777921 |
| Source note | uspto-grants-2015_07 |