6-Bromoindole-3-carbaldehyde → 6-Bromo-3-isocyanato-indole-1-carboxylic acid amide

HRID 1527173Notes

Reaction equation

HRID 1527173 reaction equation
[Br:1]C1C=C2C(C(C=O)=CN2)=CC=1.C(O[C:17]1[CH:18]=[C:19]2[C:23](=[CH:24][CH:25]=1)[N:22]([C:26]([NH2:28])=[O:27])[CH:21]=[C:20]2[N:29]=[C:30]=[O:31])C=C>>[Br:1][C:25]1[CH:24]=[C:23]2[C:19]([C:20]([N:29]=[C:30]=[O:31])=[CH:21][N:22]2[C:26]([NH2:28])=[O:27])=[CH:18][CH:17]=1

Participants

3

Reactant 2

HCID 27948306-Bromoindole-3-carbaldehydeHCID 866737945-Allyloxy-3-isocyanato-indole-1-carboxylic acid amide

Product 1

HCID 866737966-Bromo-3-isocyanato-indole-1-carboxylic acid amide

Procedure

was prepared from 6-bromo-1H-indole-3-carbaldehyde using the protocol described for steps C, D and E in scheme A4 for the preparation of 5-allyloxy-3-isocyanato-indole-1-carboxylic acid amide.

Sources & evidence

ORD record
ord-0a69f24d35094002a151a80497058171
Source dataset
uspto-grants-2015_07
Patent number
US09085555B2

Reaction notes

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