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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1527240Generated: October 30, 2026

3-(Trifluoroacetyl)indole → [3-(trifluoroacetyl)-1H-indol-1-yl]acetic acid

https://huagongshe.com/reaction/1527240

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Trifluoroacetyl)indoleHCID 589126—
Reactant(3-Acetyl-5-trifluoromethoxy-indol-1-yl)acetic acidHCID 68284505—
Product[3-(trifluoroacetyl)-1H-indol-1-yl]acetic acidHCID 3154371—

Reaction Steps

was prepared from 2,2,2-trifluoro-1-(1H-indol-3-yl)-ethanone in a similar manner as described in Scheme A13 (step B and C) for the preparation of (3-acetyl-5-trifluoromethoxy-indol-1-yl)-acetic acid. White solid. MS: 272.0 [M+H]+; tR (HPLC conditions c): 4.59 min.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09085555B2
Source datasetuspto-grants-2015_07
ORD IDord-603c5d4f58aa4b7bae41576d74402e75
Source noteuspto-grants-2015_07