Tetrahydrofuran → methyl 5-amino-4-[7-[[6-(morpholin-4-ylmethyl)-1-benzofuran-2-yl]methoxy]-3-oxo-1H-isoindol-2-yl]-5-oxopentanoate
Reaction equation
[CH2:54]1[O:55][CH2:56][CH2:57][CH2:58]1.[NH2:33][C:34]([CH:35]([CH2:36][CH2:37][C:38](=[O:39])[O:40][CH3:41])[N:42]1[C:43](=[O:52])[c:44]2[cH:45][cH:46][cH:47][c:48]([OH:51])[c:49]2[CH2:50]1)=[O:53].[O:15]1[CH2:16][CH2:17][N:18]([CH2:21][c:22]2[cH:23][c:24]3[c:25]([cH:26][c:27]([CH2:29][OH:30])[o:28]3)[cH:31][cH:32]2)[CH2:19][CH2:20]1.[O:1]=[C:2]([O:3][CH:4]([CH3:5])[CH3:6])[N:7]=[N:8][C:9]([O:10][CH:11]([CH3:12])[CH3:13])=[O:14]>>[O:15]1[CH2:16][CH2:17][N:18]([CH2:21][c:22]2[cH:23][c:24]3[c:25]([cH:26][c:27]([CH2:29][O:30][c:48]4[cH:47][cH:46][cH:45][c:44]5[c:49]4[CH2:50][N:42]([CH:35]([C:34]([NH2:33])=[O:53])[CH2:36][CH2:37][C:38](=[O:39])[O:40][CH3:41])[C:43]5=[O:52])[o:28]3)[cH:31][cH:32]2)[CH2:19][CH2:20]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-004772c9fb6c42c8872f1e4d75a629f1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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