Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1527491Generated: November 4, 2026

Hydrochloric Acid → 3-Chloro-2-fluoro-5-morpholin-4-ylmethyl-benzylamine

https://huagongshe.com/reaction/1527491

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant(3-Chloro-2-fluoro-5-morpholin-4-ylmethyl-benzyl)-carbamic acid tert-butyl esterHCID 68283950—
Solvent1,4-DioxaneHCID 31275—
Product3-Chloro-2-fluoro-5-morpholin-4-ylmethyl-benzylamineHCID 68284092—

Reaction Steps

was prepared according to Scheme C2 (step D) from (3-chloro-2-fluoro-5-morpholin-4-ylmethyl-benzyl)-carbamic acid tert-butyl ester (231 mg, 0.64 mmol) and 4N HCl in dioxane. MS (LC-MS): 259.0 [M]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09085555B2
Source datasetuspto-grants-2015_07
ORD IDord-5b4fe3c7e3ab4fedb02e3c4d825c6965
Source noteuspto-grants-2015_07