HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → N-(3-Aminomethyl-5-chloro-4-fluoro-benzyl)-N',N'-dimethyl-ethane-1,2-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | (3-Chloro-5-{[(2-dimethylamino-ethyl)-methyl-amino]-methyl}-2-fluoro-benzyl)-carbamic acid tert-butyl ester | HCID 68284327 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | N-(3-Aminomethyl-5-chloro-4-fluoro-benzyl)-N',N'-dimethyl-ethane-1,2-diamine | HCID 71009335 | — |
Reaction Steps
was prepared according to Scheme C2 (step D) from (3-chloro-5-{[(2-dimethylamino-ethyl)-methyl-amino]-methyl}-2-fluoro-benzyl)-carbamic acid tert-butyl ester (165 mg, 0.46 mmol) and 4N HCl in dioxane (3 mL). MS (LC-MS): 260.0 [M]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09085555B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-5f55a96bd60a4778bcd17c86c533ba9c |
| Source note | uspto-grants-2015_07 |