HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl (E)-3-(1,4-dimethoxy-3-methylsulfanylnaphthalen-2-yl)-2-methylpropenoate → (E)-3-(1,4-dimethoxy-3-methylsulfanylnaphthalen-2-yl)-2-methylpropenoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl (E)-3-(1,4-dimethoxy-3-methylsulfanylnaphthalen-2-yl)-2-methylpropenoate | HCID 46180104 | — |
| Reactant | (E)-3-(1,4-dimethoxynaphthalen-2-yl)-2-methylpropenoic acid | HCID 46180242 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | (E)-3-(1,4-dimethoxy-3-methylsulfanylnaphthalen-2-yl)-2-methylpropenoic acid | HCID 46180316 | — |
Reaction Steps
Compound 99h was prepared from 98h (0.165 g, 0.476 mmol) as described above for 29a to give 0.181 g (0.568 mmol, 118%) of the product as a orange solid following flash chromatography (1:3 EtOAc:hexanes 0.5% AcOH) and recrystallization from Et2O/hexanes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09089605B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-ebd4fdbc914f4b67b0196926c3bb7f31 |
| Source note | uspto-grants-2015_07 |