HuagongsheHuagongshe Chemistry Print Report · For research reference only
(E)-3-(1,4-Naphthoquinon-2-yl)-2-methylpropenoic acid → (E)-3-(3-Methyl-1,4-naphthoquinon-2-yl)-2-methylpropenoic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (E)-3-(1,4-Naphthoquinon-2-yl)-2-methylpropenoic acid | HCID 25235423 | — |
| Reactant | (E)-3-(1,4-dimethoxy-3-methylnaphthalen-2-yl)-2-methylpropenoic acid | HCID 46180244 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | (E)-3-(3-Methyl-1,4-naphthoquinon-2-yl)-2-methylpropenoic Acid | HCID 25235424 | — |
Reaction Steps
Compound 35a was prepared from 99a (0.083 g, 0.29 mmol) as described above for 30a to give 0.048 g (0.19 mmol, 65%) of the product as a yellow solid following flash chromatography (3:17 acetone:hexanes 0.5% AcOH) and recrystallization from Et2O/hexanes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09089605B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-d2753d7db2794e34816ed165381958c1 |
| Source note | uspto-grants-2015_07 |