HuagongsheHuagongshe Chemistry Print Report · For research reference only
(E)-3-(1,4-Naphthoquinon-2-yl)-2-methylpropenoic acid → (E)-3-(3-methyl-1,4-naphthoquinon-2-yl)-2-butylpropenoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (E)-3-(1,4-Naphthoquinon-2-yl)-2-methylpropenoic acid | HCID 25235423 | — |
| Reactant | (E)-3-(1,4-dimethoxy-3-methylnaphthalen-2-yl)-2-butylpropenoic acid | HCID 68769894 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | (E)-3-(3-methyl-1,4-naphthoquinon-2-yl)-2-butylpropenoic acid | HCID 25235470 | — |
Reaction Steps
Compound 35b was prepared from 99b (0.148 g, 0.45 mmol) as described above for 30a to give 0.050 g (0.17 mmol, 37%) of the product as a yellow solid following flash chromatography (2:3 Et2O:hexanes 0.5% AcOH) and recrystallization from Et2O/hexanes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09089605B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-e0b0da3331b643d38803df80b0f413b9 |
| Source note | uspto-grants-2015_07 |