HuagongsheHuagongshe Chemistry Print Report · For research reference only
(E)-3-(1,4-Naphthoquinon-2-yl)-2-methylpropenoic acid → (E)-3-(3-Methoxy-1,4-naphthoquinon-2-yl)-2-methylpropenoic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (E)-3-(1,4-Naphthoquinon-2-yl)-2-methylpropenoic acid | HCID 25235423 | — |
| Reactant | (E)-3-(1,4-dimethoxy-3-methylsulfanylnaphthalen-2-yl)-2-methylpropenoic acid | HCID 46180316 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | (E)-3-(3-Methoxy-1,4-naphthoquinon-2-yl)-2-methylpropenoic Acid | HCID 25235468 | — |
Reaction Steps
Compound 55 was prepared from 99h (0.180 g, 0.565 mmol) as described above for 30a to give 0.063 g (0.22 mmol, 38%) of the product as a red fluffy solid following flash chromatography (2:3 Et2O:hexanes 0.5% AcOH) and recrystallization from Et2O/hexanes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09089605B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-b688f82b34cb46f680d395466cb7d424 |
| Source note | uspto-grants-2015_07 |