Sodium Hydroxide → HCID 87290041, compound

HRID 1527826Notes

Reaction equation

HRID 1527826 reaction equation
C([O:3][CH:4]1[CH2:13][C:12]2[CH:11]=[CH:10][C:9]3[C:14]4[C:19]([CH:20]=[CH:21][C:8]=3[C:7]=2[O:6][CH2:5]1)=[CH:18][CH:17]=[CH:16][CH:15]=4)C.[OH-].[Na+].Cl(O)(=O)(=O)=O>>[OH:3][CH:4]1[CH2:13][C:12]2[CH:11]=[CH:10][C:9]3[C:14]4[C:19]([CH:20]=[CH:21][C:8]=3[C:7]=2[O:6][CH2:5]1)=[CH:18][CH:17]=[CH:16][CH:15]=4

Participants

4

Reactant 3

HCID 14798Sodium Hydroxide2×HCID 24247Perchloric Acid2×HCID 131733209HCID 131733209, compound5×

Product 1

HCID 87290041HCID 87290041, compound

Procedure

On other hand, 2-ethoxynaphthochroman 5a is photochemically stable and shows no decomposition even after prolonged irradiation at 254, 300 nm or 350 nm. The stability of 5a was measured in aqueous solution at pH˜7, 0.1N aqueous sodium hydroxide solution, and 0.1N aqueous perchioric acid for the 24 h period. HPLC analysis indicates that there are no changes in the concentration of 5a in aqueous solution of neutral pH and 0.1N aqueous sodium hydroxide solution. This observation clearly demonstrates that 5a is stable under neutral or basic conditions. 5a undergoes slow hydrolysis (life time τ˜9.5 h) in aqueous solution of perchloric acid of pH 1 to produce 2-hydroxynapthochroman (5e, FIG. 5). Besides, vinyl ethers are stable at ambient conditions and do not react in the dark.

Workup

  1. customeven after prolonged irradiation at 254, 300 nm or 350 nm

Sources & evidence

ORD record
ord-0bbf72fd99c94be4a35ff63c68e0e540
Source dataset
uspto-grants-2015_07
Patent number
US09090542B2

Reaction notes

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