Hydrazine hydrate (1:1) → 5-(3,4-diethoxyphenyl)-4,4-dimethyl-2,4-dihydro-3H-pyrazol-3-one

HRID 1528327Notes

Reaction equation

HRID 1528327 reaction equation
[CH2:1]([O:3][C:4]1[CH:5]=[C:6]([C:13](=O)[C:14]([CH3:20])([CH3:19])[C:15](OC)=[O:16])[CH:7]=[CH:8][C:9]=1[O:10][CH2:11][CH3:12])[CH3:2].O.[NH2:23][NH2:24]>>[CH2:1]([O:3][C:4]1[CH:5]=[C:6]([C:13]2[C:14]([CH3:20])([CH3:19])[C:15](=[O:16])[NH:23][N:24]=2)[CH:7]=[CH:8][C:9]=1[O:10][CH2:11][CH3:12])[CH3:2]

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 66616533Methyl 3-(3,4-diethoxyphenyl)-2,2-dimethyl-3-oxopropanoate2×

Product 1

HCID 666164935-(3,4-diethoxyphenyl)-4,4-dimethyl-2,4-dihydro-3H-pyrazol-3-one

Procedure

Prepared analogously as described for example C1 using methyl 3-(3,4-diethoxyphenyl)-2,2-dimethyl-3-oxopropanoate (compound D2) and hydrazine hydrate as starting compounds.

Workup

  1. customPrepared analogously

Sources & evidence

ORD record
ord-27b3faf2398c49a1858c9462117c8e62
Source dataset
uspto-grants-2015_07
Patent number
US09090597B2

Reaction notes

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