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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1528397Generated: October 26, 2026

(4-Chloro-3-methylphenyl)boronic acid → 5-(4-Chloro-3-methylphenyl)-6-cyclobutoxynicotinic acid

https://huagongshe.com/reaction/1528397

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Chloro-3-methylphenyl)boronic acidHCID 3786632—
ReactantHCID 66678843HCID 66678843—
Product5-(4-Chloro-3-methylphenyl)-6-cyclobutoxynicotinic acidHCID 66678489—

Reaction Steps

The title compound was synthesized in analogy to Example BQ using 5-bromo-6-cyclobutoxy-nicotinic acid (example BY) and B-(4-chloro-3-methylphenyl)-boronic acid (CAN 161950-10-3) as starting materials; MS (ESI): 316.2 (M−H)−.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09090599B2
Source datasetuspto-grants-2015_07
ORD IDord-e569bd2b3a484ebcbc970781d20fd73b
Source noteuspto-grants-2015_07