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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1528404Generated: October 31, 2026

Tetrahydro-3-furanmethanol → 5-(4-Chloro-phenyl)-6-(tetrahydro-furan-3-ylmethoxy)-nicotinic acid

https://huagongshe.com/reaction/1528404

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydro-3-furanmethanolHCID 139980—
Reactant6-Chloro-5-(4-chlorophenyl)-3-pyridinecarboxylic acidHCID 86619183—
Product5-(4-Chloro-phenyl)-6-(tetrahydro-furan-3-ylmethoxy)-nicotinic acidHCID 66678490—

Reaction Steps

The title compound was synthesized in analogy to Example CI using 6-chloro-5-(4-chlorophenyl)-3-pyridine carboxylic acid (CAN 1012792-56-1) and tetrahydro-3-furanmethanol (CAN 15833-61-1) as starting materials; LC-MS (UV peak area/ESI) 91.6%, 334.0833 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09090599B2
Source datasetuspto-grants-2015_07
ORD IDord-b070a593c7a54b4fa88843c35c0ff2f5
Source noteuspto-grants-2015_07