Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | HCID 66578386 | HCID 66578386 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 66578155 | HCID 66578155 | — |
Reaction Steps
1-{4′-[3-Methyl-4-(3-methyl-butyrylamino)-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl ester (0.060 g, 0.13 mmol) in MeOH and H2O was treated with lithium hydroxide (0.100 g, 2.4 mmol) and stirred at 60° C. for 1 hour. The mixture was submitted to standard workup to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09090573B2 |
|---|
| Source dataset | uspto-grants-2015_07 |
|---|
| ORD ID | ord-91e4f41c982544108b77cf71f84679e6 |
|---|
| Source note | uspto-grants-2015_07 |
|---|
