反应详情

温度

85 °C

1-{4′-[4-(Benzyloxycarbonylamino-methyl)-3-methyl-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl ester (0.462 g, 0.90 mmol) was treated with trifluoroacetic acid (10 mL) and the reaction was stirred at 85° C. for 1 hour. The mixture was concentrated to give the title compound.

1. concentrationThe mixture was concentrated