Tetrabutylammonium Fluoride → HCID 86673640, compound

HRID 1528862Notes

Reaction equation

HRID 1528862 reaction equation
[CH2:1]([O:3][C:4]([C:6]1([C:9]2[CH:14]=[CH:13][C:12]([C:15]3[CH:20]=[CH:19][C:18]([C:21]4[O:25][N:24]=[C:23]([CH3:26])[C:22]=4[CH2:27][S:28][Si](C(C)C)(C(C)C)C(C)C)=[CH:17][CH:16]=3)=[CH:11][CH:10]=2)[CH2:8][CH2:7]1)=[O:5])[CH3:2].[F-].C([N+](CCCC)(CCCC)CCCC)CCC>C1COCC1>[CH2:1]([O:3][C:4]([C:6]1([C:9]2[CH:10]=[CH:11][C:12]([C:15]3[CH:20]=[CH:19][C:18]([C:21]4[O:25][N:24]=[C:23]([CH3:26])[C:22]=4[CH2:27][SH:28])=[CH:17][CH:16]=3)=[CH:13][CH:14]=2)[CH2:8][CH2:7]1)=[O:5])[CH3:2]

Participants

4

Reactant 2

HCID 2724141Tetrabutylammonium FluorideHCID 66580466HCID 66580466, compound

Product 1

HCID 86673640HCID 86673640, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

The mixture from Step 1 was dissolved in THF and tetrabutylammonium fluoride (1.0 M in THF, 2.27 mL, 2.27 mmol) was added. The reaction stirred for 5 minutes and was then submitted to standard aqueous workup and purification via silica gel chromatography to yield the title compound.

Workup

  1. customwas then submitted to standard aqueous workup and purification via silica gel chromatography

Sources & evidence

ORD record
ord-0ea61de36b214104b1ee4e98f579d92a
Source dataset
uspto-grants-2015_07
Patent number
US09090573B2

Reaction notes

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