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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1528903Generated: November 3, 2026

Cyclopentyl Isocyanate → HCID 66578103, compound

https://huagongshe.com/reaction/1528903

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopentyl IsocyanateHCID 643500—
Reactant[5-(4-Bromo-phenyl)-3-methyl-isoxazol-4-yl]-methanolHCID 58218538—
SolventTolueneHCID 1140—
ProductHCID 66578103HCID 66578103—

Reaction Conditions

Temperature120 °C

Reaction Steps

[5-(4-Bromo-phenyl)-3-methyl-isoxazol-4-yl]-methanol (0.120 g, 0.45 mmol) was mixed with cyclopentyl isocyanate (0.075 g, 0.68 mmol) in toluene and the reaction was heated to 120° C. overnight. After cooling, the crude material was submitted directly to silica gel purification to afford the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09090573B2
Source datasetuspto-grants-2015_07
ORD IDord-ce8410e55957447d9ab320e16f885dd7
Source noteuspto-grants-2015_07