HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[3-(Trifluoromethyl)phenyl]butan-2-one → (4'-{3-Methyl-4-[1-methyl-3-(3-trifluoromethyl-phenyl)-propylamino]-isoxazol-5-yl}-biphenyl-4-yl)-acetic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[3-(Trifluoromethyl)phenyl]butan-2-one | HCID 13339059 | — |
| Reactant | Ethyl 2-(4'-(4-amino-3-methylisoxazol-5-yl)-[1,1'-biphenyl]-4-yl)acetate | HCID 66577589 | — |
| Product | (4'-{3-Methyl-4-[1-methyl-3-(3-trifluoromethyl-phenyl)-propylamino]-isoxazol-5-yl}-biphenyl-4-yl)-acetic acid ethyl ester | HCID 66582074 | — |
Reaction Steps
Prepared according to the procedure described in Example 24, Step 1, using [4′-(4-amino-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]acetic acid ethyl ester and 4-(3-trifluoromethyl-phenyl)-butan-2-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09090573B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-a97ca043094f43d4b35c1791ce3a62c9 |
| Source note | uspto-grants-2015_07 |