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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1528939Generated: October 30, 2026

4-(3-Chlorophenyl)butan-2-one → (4'-{4-[3-(3-Chloro-phenyl)-1-methyl-propylamino]-3-methyl-isoxazol-5-yl}-biphenyl-4-yl)-acetic acid ethyl ester

https://huagongshe.com/reaction/1528939

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(3-Chlorophenyl)butan-2-oneHCID 260432—
ReactantEthyl 2-(4'-(4-amino-3-methylisoxazol-5-yl)-[1,1'-biphenyl]-4-yl)acetateHCID 66577589—
Product(4'-{4-[3-(3-Chloro-phenyl)-1-methyl-propylamino]-3-methyl-isoxazol-5-yl}-biphenyl-4-yl)-acetic acid ethyl esterHCID 66578083—

Reaction Steps

Prepared according to the procedure described in Example 24, Step 1, using [4′-(4-amino-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-acetic acid ethyl ester and 4-(3-chloro-phenyl)-butan-2-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09090573B2
Source datasetuspto-grants-2015_07
ORD IDord-616e4cd07b3e4a8389831e3b0aa86ede
Source noteuspto-grants-2015_07