5-Hydroxy-2-pentanone → 4-[5-(4-Bromo-phenyl)-3-methyl-isoxazol-4-ylamino]-pentan-1-ol

HRID 1529005Notes

Reaction equation

HRID 1529005 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:12][N:11]=[C:10]([CH3:13])[C:9]=2[NH2:14])=[CH:4][CH:3]=1.[OH:15][CH2:16][CH2:17][CH2:18][C:19](=O)[CH3:20]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[O:12][N:11]=[C:10]([CH3:13])[C:9]=2[NH:14][CH:19]([CH3:20])[CH2:18][CH2:17][CH2:16][OH:15])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 140665-Hydroxy-2-pentanoneHCID 582185375-(4-Bromophenyl)-3-methylisoxazol-4-amine

Product 1

HCID 665782724-[5-(4-Bromo-phenyl)-3-methyl-isoxazol-4-ylamino]-pentan-1-ol

Procedure

Prepared according to the procedure described in Example 24, Step 1, using 5-(4-bromo-phenyl)-3-methyl-isoxazol-4-ylamine and 5-hydroxy-pentan-2-one.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-f2f47cbbbcd744638720a43fd1c78d28
Source dataset
uspto-grants-2015_07
Patent number
US09090573B2

Reaction notes

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