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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1529008Generated: November 2, 2026

Ethyl 2-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)phenyl)acetate → {4'-[4-(4-Hydroxy-1-methyl-butylamino)-3-methyl-isoxazol-5-yl]-biphenyl-2-yl}-acetic acid ethyl ester

https://huagongshe.com/reaction/1529008

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)phenyl)acetateHCID 58539376—
Reactant4-[5-(4-Bromo-phenyl)-3-methyl-isoxazol-4-ylamino]-pentan-1-olHCID 66578272—
Product{4'-[4-(4-Hydroxy-1-methyl-butylamino)-3-methyl-isoxazol-5-yl]-biphenyl-2-yl}-acetic acid ethyl esterHCID 66582070—

Reaction Steps

Prepared according to the procedure described in Example 1, Step 7, using 4-[5-(4-bromo-phenyl)-3-methyl-isoxazol-4-ylamino]-pentan-1-ol and [2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-acetic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09090573B2
Source datasetuspto-grants-2015_07
ORD IDord-67bb6f5616dd48c08b2fcf48b4aeec74
Source noteuspto-grants-2015_07