Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → 5-ethynyl-N-methylpyridin-2-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | Methyl-(5-trimethylsilanylethynyl-pyridin-2-yl)-amine | HCID 66705950 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 5-ethynyl-N-methylpyridin-2-amine | HCID 22663128 | — |
반응 단계
The title compound is synthesized according to general procedure GP3 starting from 1.5 g (7.3 mmol) methyl-(5-trimethylsilanylethynyl-pyridin-2-yl)-amine (A6) and 507 mg (3.7 mmol) K2CO3 in 10 mL MeOH. Yield: 698 mg (56%) after chromatography on silica gel.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09090564B2 |
| 출처 데이터셋 | uspto-grants-2015_07 |
| ORD ID | ord-bc6b3ed0855547b995134c3c3f7a7666 |
| 출처 메모 | uspto-grants-2015_07 |