Dichloromethane → [4-(4-Aminobutyl)phenoxy]acetonitrile

HRID 152949Notes

Reaction equation

HRID 152949 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][CH2:8][CH2:9][CH2:10][CH2:11][c:12]1[cH:13][cH:14][c:15]([O:18][CH2:19][C:20]#[N:21])[cH:16][cH:17]1)([CH3:5])([CH3:6])[CH3:22].[Cl:30][CH2:31][Cl:32].[OH:23][C:24]([C:25]([F:26])([F:27])[F:28])=[O:29]>>[NH2:7][CH2:8][CH2:9][CH2:10][CH2:11][c:12]1[cH:13][cH:14][c:15]([O:18][CH2:19][C:20]#[N:21])[cH:16][cH:17]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 21031133[4-(4-Cyanomethoxyphenyl)butyl]carbamic acid tert-butyl ester

Product 1

HCID 22054440[4-(4-Aminobutyl)phenoxy]acetonitrile

Sources & evidence

ORD record
ord-efc3e0d355fa490492411bd642b098cb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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