Succinimide → HCID 71001893, compound

HRID 1530186Notes

Reaction equation

HRID 1530186 reaction equation
[C:1]1(=[O:7])[NH:5][C:4](=[O:6])[CH2:3][CH2:2]1.[C:8]([O:16]CC)(=O)[C:9]1[CH:14]=[CH:13][CH:12]=[N:11][CH:10]=1>>[C:4]1(=[O:6])[NH:5][C:1](=[O:7])[CH2:2][CH2:3]1.[C:8]([NH2:5])(=[O:16])[C:9]1[CH:14]=[CH:13][CH:12]=[N:11][CH:10]=1

Participants

3

Reactant 2

HCID 11439SuccinimideHCID 69188Ethyl Nicotinate

Product 1

HCID 71001893HCID 71001893, compoundYield 5,075.4%

Conditions

Temperature
150 °C

Procedure

Succinimide (2100 number average molecular weight, 368.8 g, 0.073 mol) and ethyl nicotinate (16.6 g, 0.11 mol) were charged to a 250 mL resin kettle equipped with an overhead stirrer, a Dean-Stark trap and a thermocouple. The reaction mixture was heated under a nitrogen atmosphere to 150° C. for 3 hours. The reaction mixture was diluted with 44.6 g process oil to afford 409.8 g of desired product.

Workup

  1. customequipped with an overhead stirrer
  2. additionThe reaction mixture was diluted with 44.6 g process oil

Sources & evidence

ORD record
ord-35b2d011b5a041a4a4ee02ed976f662c
Source dataset
uspto-grants-2015_07
Patent number
US09090847B2

Reaction notes

Loading…