Dimethylformamide → HCID 68312737, compound

Participants

Reaction Steps

2-(1-isopropyl-1H-1,2,4-triazol-5-yl)-5,6-dihydroimidazo[1,2-d]pyrido[4,3-f][1,4]oxazepine-10-carbaldehyde (0.250 g, 0.771 mmol) was dissolved in N,N-Dimethylformamide (2 mL, 0.02 mol). Oxone® (0.569 g, 0.925 mmol) was added and the reaction mixture was stirred overnight at room temperature. A light-brown precipitate formed and was collected by filtration. LC-MS analysis verified precipitate as desired product, 2-(1-isopropyl-1H-1,2,4-triazol-5-yl)-5,6-dihydroimidazo[1,2-d]pyrido[4,3-f][1,4]oxazepine-10-carboxylic acid which was carried on without further purification.

Provenance & Evidence