HuagongsheHuagongshe Chemistry Print Report · For research reference only
Roxithromycin → HCID 178455840, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Roxithromycin | HCID 6915744 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 178455840 | HCID 178455840 | — |
Reaction Steps
Roxithromycin (30 grams) was dissolved in a solution of Eudragit RS100 (70 grams) in methylene chloride (560 grams). The solution was pumped through an atomising nozzle into a spray drier with an inlet air temperature of 55° C. The powder was collected and suspended in a 0.05M glycine buffer at pH 10 containing 1% polyvinylpyrollidone. The taste due to the roxithromycin was not detectable 5 days after preparation.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06197348B1 |
| Source dataset | uspto-grants-2001_03 |
| ORD ID | ord-767b984824324bc7ba21e9cfd952d031 |
| Source note | uspto-grants-2001_03 |