Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Nitrite | HCID 23668193 | — |
| Reactant | HCID 70118589 | HCID 70118589 | — |
| Solvent | Acetone | HCID 180 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 70118057 | HCID 70118057 | 35% |
Reaction Steps
The 2-(vinyltrityl)-3-aminophenol is dissolved in a 50/50 solution of acetone and 50% H2PO3. The solution is chilled to 0° C. NaNO2 (1.0 g, 2.0 equiv.) is dissolved in water (10 mL) and added at a rate to keep the temperature of the reaction mixture below 5° C. The mixture is stirred for an additional 30 minutes. The product 2-(vinyltrityl)phenol is obtained by filtration and dried under vacuum (yield 35-45%). Product is recrystallized from hot acetic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06197715B1 |
|---|
| Source dataset | uspto-grants-2001_03 |
|---|
| ORD ID | ord-5ec0fcd0d5734a79b49654114616ef2c |
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| Source note | uspto-grants-2001_03 |
|---|
