反应详情

A solution of 4-hydroxybenzenesulfonic acid (6.5 grams, 28.2 mmole) and sodium hydroxide (2.2 grams, 55 mmole) in water (15 mL) was mixed with a solution of 2-(bromoethyl)cyclopentane (15.0 grams, 84.7 mmole) in isopropanol (40 mL) and the resulting mixture was heated at reflux for 2 days. The isopropanol was removed by evaporation under vacuum. The titled compound, 4.7 grams (57%), was collected by filtration and washed with isopropanol.

1. temperaturethe resulting mixture was heated
2. temperatureat reflux for 2 days
3. customThe isopropanol was removed by evaporation under vacuum
4. filtrationThe titled compound, 4.7 grams (57%), was collected by filtration
5. washwashed with isopropanol