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HRID1531237

反应详情

EQUATION

反应方程式

HRID 1531237 的结构方程式

REACTANTS

反应物

2
结构：[BH4-].[Na+]
HCID4311764

Sodium borohydride (Na(BH4))

H4BNa

结构：CCCC(=O)C(F)(F)CC=C[C@@H]1[C@H]2CC(=O)O[C@H]2C[C@H]1OC1CCCCO1
HCID69112797

未命名化合物

PRODUCTS

生成物

1
结构：CCCC(O)C(F)(F)CCC[C@@H]1[C@H]2CC(=O)O[C@H]2C[C@H]1OC1CCCCO1
HCID22842860

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

Sodium borohydride (0.800 g) was added to the solution of (1S,5R,6R,7R)-6-(4,4-difluoro-5-oxo-octenyl)-7-tetrahydropyranyloxy-2-oxabicyclo[3.3.0]-octan-3-one (5) (5.48 g) in methanol at 0° C., and stirred for 10 minutes. The reaction product was treated with a usual manner, and the obtained crude product was subjected to column chromatography to give a titled compound (6). Yield: 5.46 g (99.5%)

WORKUP

后处理

  1. additionThe reaction product was treated with a usual manner
  2. customthe obtained crude product