N-tert-butylhydroxylamine → HCID 178449916, compound

HRID 1531241Notes

Reaction equation

HRID 1531241 reaction equation
[F:1][C:2]1[C:3]([OH:10])=[C:4]([CH:7]=[CH:8][CH:9]=1)[CH:5]=O.[C:11]([NH:15][OH:16])([CH3:14])([CH3:13])[CH3:12]>>[F:1][C:2]1[C:3]([OH:10])=[C:4]([CH:5]=[N+:15]([C:11]([CH3:14])([CH3:13])[CH3:12])[O-:16])[CH:7]=[CH:8][CH:9]=1

Participants

3

Reactant 2

HCID 98586N-tert-butylhydroxylamineHCID 5877883-Fluorosalicylaldehyde

Product 1

HCID 178449916HCID 178449916, compound

Procedure

The title compound was prepared according to the procedure described in Example 1 using 3-fluoro-2-hydroxybenzaldehyde and N-tert-butylhydroxylamine. The title compound was isolated in 92.7% yield as a yellow crystalline solid, m.p. 70.3° C. (Rf=0.25 on a silica gel plate using 7:3 hexanes/EtOAc as an eluant).

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-b624a19ca4144cbdbb4f1f90907f9131
Source dataset
uspto-grants-2001_03
Patent number
US06197826B1

Reaction notes

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