O-Ethylvanillin → HCID 178466537, compound

HRID 1531245Notes

Reaction equation

HRID 1531245 reaction equation
[CH2:1]([O:3][C:4]1[C:5]([OH:12])=[C:6]([CH:9]=[CH:10][CH:11]=1)[CH:7]=O)[CH3:2].[C:13]([NH:17][OH:18])([CH3:16])([CH3:15])[CH3:14]>>[CH2:1]([O:3][C:4]1[C:5]([OH:12])=[C:6]([CH:7]=[N+:17]([C:13]([CH3:16])([CH3:15])[CH3:14])[O-:18])[CH:9]=[CH:10][CH:11]=1)[CH3:2]

Participants

3

Reactant 2

HCID 68117O-EthylvanillinHCID 98586N-tert-butylhydroxylamine

Product 1

HCID 178466537HCID 178466537, compound

Procedure

The title compound was prepared according to the procedure described in Example 13 using 3-ethoxy-2-hydroxybenzaldehyde and N-tert-butylhydroxylamine. The title compound was isolated in 36.4% yield as a yellow crystalline solid, m.p. 91.9° C. (Rf=0.25 on a silica gel plate using 1:1 EtOAc/hexanes as an eluant).

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-22c1535b0c694e0c8b939630a8b5d84a
Source dataset
uspto-grants-2001_03
Patent number
US06197826B1

Reaction notes

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