4,6-Dimethoxysalicylaldehyde → HCID 178493531, compound

HRID 1531249Notes

Reaction equation

HRID 1531249 reaction equation
[CH3:1][O:2][C:3]1[CH:10]=[C:9]([O:11][CH3:12])[C:6]([CH:7]=O)=[C:5]([OH:13])[CH:4]=1.[C:14]([NH:18][OH:19])([CH3:17])([CH3:16])[CH3:15]>>[CH3:1][O:2][C:3]1[CH:10]=[C:9]([O:11][CH3:12])[C:6]([CH:7]=[N+:18]([C:14]([CH3:17])([CH3:16])[CH3:15])[O-:19])=[C:5]([OH:13])[CH:4]=1

Participants

3

Reactant 2

HCID 697254,6-DimethoxysalicylaldehydeHCID 98586N-tert-butylhydroxylamine

Product 1

HCID 178493531HCID 178493531, compound

Procedure

The title compound was prepared according to the procedure described in Example 1 using 4,6-dimethoxy-2-hydroxybenzaldehyde and N-tert-butylhydroxylamine. The title compound was isolated in 60.7% yield as a yellow crystalline solid, m.p. 97.3° C. (Rf=0.38 on a silica gel plate using 7:3 hexanes/EtOAc as an eluant).

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-0715159da3fc4c86bc6daa5e69d04129
Source dataset
uspto-grants-2001_03
Patent number
US06197826B1

Reaction notes

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