Dimethyl Sulfate → HCID 86756514, compound

HRID 1531441Notes

Reaction equation

[CH3:1][O:2][NH:3][C:4](=[O:24])[C:5]1[CH:10]=[C:9]([C:11]2[C:15]([F:16])=[C:14]([O:17][CH:18]([F:20])[F:19])[N:13]([CH3:21])[N:12]=2)[C:8]([Cl:22])=[CH:7][C:6]=1[Cl:23].[C:25](=O)([O-])[O-].[K+].[K+].S(OC)(OC)(=O)=O>>[CH3:1][O:2][N:3]=[C:4]([O:24][CH3:25])[C:5]1[CH:10]=[C:9]([C:11]2[C:15]([F:16])=[C:14]([O:17][CH:18]([F:20])[F:19])[N:13]([CH3:21])[N:12]=2)[C:8]([Cl:22])=[CH:7][C:6]=1[Cl:23]

Participants

Reactant 3

HCID 6497Dimethyl Sulfate

HCID 11430Potassium Carbonate

HCID 21254039HCID 21254039, compound

Product 1

HCID 86756514HCID 86756514, compound

Procedure

Using 0.5 g (1.3 mmol) of N-methoxy-2,4-dichloro-5-(5-difluoromethoxy-4-fluoro-1-methyl-1H-pyrazol-3-yl)benzamide, 0.21 g (1.6 mmol) of potassium carbonate and 0.20 g (1.6 mmol) of dimethyl sulfate and following the procedure described in Example 1, 0.17 g of the desired produce of value was obtained.

Workup

customdesired produce of value
customwas obtained

Sources & evidence

ORD record: ord-c85262a2718a416e86c5b054c2291e9b
Source dataset: uspto-grants-2001_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06197973B1

Reaction notes

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