Oxalyl chloride → HCID 21254023, compound

HRID 1531444Notes

Reaction equation

[Cl:1][C:2]1[CH:10]=[C:9]([Cl:11])[C:8]([C:12]2[C:16]([F:17])=[C:15]([O:18][CH:19](F)[F:20])[N:14]([CH3:22])[N:13]=2)=[CH:7][C:3]=1[C:4](O)=[O:5].C(Cl)(=O)C([Cl:26])=O>>[Cl:1][C:2]1[CH:10]=[C:9]([Cl:11])[C:8]([C:12]2[C:16]([F:17])=[C:15]([O:18][CH2:19][F:20])[N:14]([CH3:22])[N:13]=2)=[CH:7][C:3]=1[C:4]([Cl:26])=[O:5]

Participants

Reactant 2

HCID 65578Oxalyl chloride

HCID 15672382HCID 15672382, compound

Product 1

HCID 21254023HCID 21254023, compound

Procedure

5.8 g (16 mmol) of 2,4-dichloro-5-(5-difluoromethoxy-4-fluoro-1-methyl-1H-pyrazol-3-yl)benzoic acid and 10.4 g (82 mmol) of oxalyl chloride were reacted in the manner described for Precursor 1.1. Yield: 5.2 g.

Sources & evidence

ORD record: ord-b33b5e43d50f403e9ec06c35f4b0302e
Source dataset: uspto-grants-2001_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06197973B1

Reaction notes

Loading…